Spinal Fusion Surgery Naples FL | Dr. Mark Frenkel MD

Spinal Fusion Surgery Naples FL | Dr. Mark Frenkel MD
Naples, Florida · Southwest Florida · Nationwide Concierge Program

Spinal Fusion Surgery from the
Surgeon Who Reinvented It

Dr. Mark Frenkel didn’t just train in spinal fusion — he invented a new way to perform it. As the creator of CemLIF™, the world’s first rod-less, screw-less lumbar fusion technique, he brings surgical innovation available nowhere else to patients in Naples, Florida and across the country.

Inventor of CemLIF™
Board-Certified Neurosurgeon
Castle Connolly Top Doctor 2024–2026
Telehealth Available
MF
Dr. Mark B. Frenkel
MD, MA, FAANS, FCNS
Neurosurgeon & Spine Surgeon
Neuroscience and Spine Associates
Inventor of CemLIF™ — Rod-Less Fusion
99th
Healthgrades Percentile
Castle Connolly Top Doctor
7yr
Neurosurgery Residency
5★
Google & Healthgrades
🔒 HIPAA Compliant · Secure & Private · Accepting New Patients
Castle Connolly Top Doctor 2024–2026
Healthgrades 99th Percentile
Inventor — CemLIF™ Rod-Less Lumbar Fusion
Complex & Revision Cases Accepted
Concierge Program — Nationwide
Dr. Frenkel’s Patented Innovation

CemLIF™ — The Lumbar Fusion
Dr. Frenkel Invented

CemLIF™ (Cement Lumbar Interbody Fusion) is a rod-less, screw-less lumbar fusion technique patented by Dr. Mark Frenkel — a paradigm shift in how the spine is stabilized and fused. No other surgeon or practice in the world offers this procedure.

  • No rods. No pedicle screws. Eliminates the hardware bulk and implant-related complications associated with traditional fusion constructs
  • Highly stable fusion achieved through an innovative cement-based interbody technique developed exclusively by Dr. Frenkel
  • Multiple patents pending — Dr. Frenkel continues to advance the technique with new instruments and implant designs
  • Featured on WINK News as a breakthrough innovation in lumbar spine surgery
  • Appropriate for selected patients with lumbar instability, spondylolisthesis, and stenosis requiring fusion

CemLIF™ vs. Traditional Lumbar Fusion

Traditional Fusion
Pedicle screws & titanium rods
Extensive hardware implantation
Potential hardware-related complications
Hardware revision risk
CemLIF™
Rod-free construct
Screw-free technique
Highly stable fusion
Only at Dr. Frenkel’s practice

Whether CemLIF™ is appropriate for your specific anatomy and diagnosis is determined during a thorough consultation and imaging review with Dr. Frenkel.

Fusion Procedures Performed

Every Spinal Fusion Approach — Explained Simply

Spinal fusion can be performed through multiple surgical approaches, each suited to different spinal levels, anatomy, and clinical indications. Dr. Frenkel selects the most appropriate technique for each patient individually — including his own patented CemLIF™ for selected lumbar cases.

CemLIF™
Cement Lumbar Interbody Fusion · Dr. Frenkel’s Patent
Exclusive to Dr. Frenkel

A revolutionary rod-less, screw-less lumbar fusion invented by Dr. Frenkel. Delivers highly stable fusion without traditional hardware implants. Available exclusively at Dr. Frenkel’s practice. cemlif.com →

Approach: Minimally invasive lumbar
Levels: Lumbar spine
Unique to: Dr. Frenkel’s practice only
ALIF
Anterior Lumbar Interbody Fusion
Lumbar Spine

Spine accessed from the front (anterior) through a small abdominal incision. Allows placement of a large interbody device, excellent disc height restoration, and significant lumbar lordosis correction. Muscles are not disrupted.

Approach: Anterior (front)
Best for: L4–L5, L5–S1; degenerative disc disease, spondylolisthesis
Advantage: Large implant, no posterior muscle disruption
LLIF / XLIF
Lateral Lumbar Interbody Fusion
Lumbar Spine

Minimally invasive approach through the patient’s flank — the spine is accessed laterally, avoiding both the back muscles and the abdominal vessels. Excellent for multi-level disease and deformity correction.

Approach: Lateral (side)
Best for: Multi-level disease, scoliosis, L1–L4 levels
Advantage: Minimal blood loss; muscle-sparing
PLIF
Posterior Lumbar Interbody Fusion
Lumbar Spine

Posterior approach through the back. Includes removal of the lamina (laminectomy) and facet joints to access the disc space. Can be performed minimally invasively. Effective for stenosis with instability.

Approach: Posterior (back)
Best for: Spondylolisthesis, stenosis, recurrent disc herniation
Also: TLIF (transforaminal variant) — less nerve retraction
ACDF
Anterior Cervical Discectomy & Fusion
Cervical Spine

The most common cervical spine fusion — performed through a small incision in the front of the neck. The herniated disc or bone spurs are removed, and the adjacent vertebrae are fused using a bone graft and metal plate.

Approach: Anterior cervical
Best for: Cervical disc herniation, cervical stenosis, myelopathy
Success: High — widely studied with excellent outcomes
Robotic
Robotic-Assisted Spinal Surgery
All Fusion Types

Dr. Frenkel uses robotic assistance, computer navigation, and his own augmented reality navigation system for all complex fusion procedures — delivering accuracy that exceeds freehand techniques and significantly reduces risk in multi-level and revision cases.

Technology: Robotic + AR navigation (Dr. Frenkel’s own system)
Advantage: Sub-millimeter precision in instrumentation placement
Dr. Frenkel’s Approach

What Sets Dr. Frenkel’s Spinal Fusion Practice Apart

You’ll Receive a Diagnosis Before a Recommendation

Many patients arrive after seeing other surgeons who recommended fusion without a thorough review of their imaging, their neurological exam, or their lifestyle and goals. Dr. Frenkel starts every consultation with a complete review of your MRI, CT, and X-ray imaging combined with an in-depth physical examination.

You will understand your condition, the reason fusion is or is not appropriate, and exactly what to expect — before any surgical recommendation is made.

Minimally Invasive — Always the Preferred Approach

Open fusion surgery traditionally involves large incisions, significant muscle disruption, and lengthy recovery. Dr. Frenkel uses minimally invasive techniques whenever anatomically appropriate — tubular retractors, endoscopic instruments, lateral approaches, and anterolateral approaches that preserve surrounding musculature.

The result is meaningfully less post-operative pain, reduced hospital stay, and faster return to daily life compared to traditional open fusion approaches.

Only Here: CemLIF™ Rod-Less Lumbar Fusion. For appropriate lumbar fusion candidates, Dr. Frenkel may offer his patented CemLIF™ technique — a rod-less, screw-less fusion unavailable at any other surgical practice. Whether CemLIF™ is appropriate for your anatomy is determined at consultation. Learn more at cemlif.com →

Precision Technology: AR Navigation + Robotics

Dr. Frenkel was the first surgeon in the world to use augmented reality intraoperatively for spinal navigation — a system he developed himself. Combined with robotic assistance and computer-guided planning, this allows instrumentation placement at sub-millimeter precision — critical in complex multi-level fusion, revision cases, and procedures near the spinal cord.

Conditions That May Require Spinal Fusion

Fusion is typically recommended when spinal instability — not just nerve compression — is part of the problem. Common indications include:

  • →  Spondylolisthesis (vertebral slippage)
  • →  Degenerative disc disease with spinal instability
  • →  Spinal stenosis with associated instability
  • →  Scoliosis and complex spinal deformity
  • →  Failed prior spinal surgery requiring revision
  • →  Cervical disc herniation with myelopathy (ACDF)
Medical Disclaimer: The information on this page is for educational purposes only and does not constitute medical advice. All surgical and treatment decisions are made on an individualized basis following a thorough consultation with Dr. Frenkel. Results may vary. Always consult a qualified physician before pursuing any surgical or medical treatment.
Fusion Procedures Dr. Frenkel Performs
  • CemLIF™ — Rod-Less, Screw-Less Lumbar Fusion (Dr. Frenkel’s Patent)
  • ALIF — Anterior Lumbar Interbody Fusion
  • PLIF — Posterior Lumbar Interbody Fusion
  • LLIF / XLIF — Lateral Lumbar Interbody Fusion
  • ACDF — Anterior Cervical Discectomy & Fusion
  • TOPS™ Posterior Arthroplasty (motion-preserving)
  • ACDA — Cervical Disc Arthroplasty
  • Robotic-Assisted Spinal Fusion
  • Complex Multi-Level Deformity Reconstruction
  • Revision Fusion Surgery
View All Procedures →
Conditions That May Require Fusion
  • Spondylolisthesis
  • Degenerative Disc Disease
  • Lumbar & Cervical Spinal Stenosis with Instability
  • Scoliosis & Complex Deformity
  • Cervical Disc Herniation / Myelopathy
  • Failed Prior Fusion (Revision Surgery)
  • Spinal Tumors
  • Spinal Fractures
View All Conditions →
Second Opinion Welcome

If another surgeon has recommended fusion and you want a second opinion — or if a prior fusion hasn’t provided the relief you were promised — Dr. Frenkel welcomes complex cases and revision patients. No referral needed.

Request a Second Opinion
Why Choose Dr. Frenkel

The Credentials, Innovation, and Experience Your Spine Deserves

When you’re choosing a spinal fusion surgeon, generic claims of “expertise” are not enough. Here are the specific, verifiable reasons patients travel from across Florida and nationwide to choose Dr. Frenkel.

He Invented a New Way to Fuse the Spine

Dr. Frenkel is the inventor of CemLIF™ — a patented rod-less, screw-less lumbar fusion technique that represents a paradigm shift in spinal surgery. He also developed the world’s first augmented reality intraoperative navigation system. These innovations are available exclusively at his practice. cemlif.com →

Academic Training at the Highest Level

Case Western Reserve University School of Medicine (Cleveland Clinic-affiliated) — Honors and Distinction in Research. Seven-year neurosurgery residency at Wake Forest University under a pioneer in spinal surgery. Chief Resident for two consecutive years — a rare distinction. Mentors trained at Harvard and Johns Hopkins.

The Surgeon Other Surgeons Refer To

Dr. Frenkel regularly receives referrals from other spine and orthopedic surgeons for complex multi-level fusion, failed prior fusion, and spinal deformity reconstruction. If another surgeon has turned down your case or a prior fusion has failed, Dr. Frenkel has the training and technology to evaluate your options.

Personalized — Not Protocol-Driven

Every patient receives a complete imaging review, thorough physical examination, and a treatment strategy built around their specific anatomy, spinal level, age, activity goals, and overall health. Dr. Frenkel will not recommend fusion unless it is genuinely the best option for your situation.

Concierge Program for Traveling Patients

Distance is no obstacle to world-class spinal fusion care. Dr. Frenkel’s Concierge Spinal Surgery Program provides telehealth consultations, travel coordination, VIP clinic access, and fully transparent cost information for patients from other states or countries seeking access to CemLIF™ and his full surgical portfolio.

Credentials & Recognition

Recognized as One of the Nation’s Leading Spine Surgeons

Every credential listed below is specific and verifiable — the standard required for YMYL medical content.

Education & Training

  • MD, MA — Case Western Reserve University School of Medicine (Cleveland Clinic-affiliated) — Honors and Distinction in Research
  • 7-Year Neurosurgery Residency — Wake Forest University, under Dr. Charles Branch (pioneer in spinal surgery)
  • Chief Resident — two consecutive years — a rare distinction
  • Mentors trained at Harvard and Johns Hopkins
  • One of the highest Neurosurgery Board scores in the country
  • 2018 CNS SANS Challenge Winner — national neurosurgical competition

Awards, Innovation & Affiliations

  • Castle Connolly Top Doctors: 2024, 2025, 2026
  • Healthgrades 99th Percentile — Top-Rated Spine Surgeon in Naples FL
  • Naples Illustrated Top Doctor — multiple consecutive years
  • Inventor of CemLIF™ | Multiple patents pending | First surgeon to use augmented reality in spinal navigation
  • Peer-reviewed: Journal of Neurosurgery: Spine, World Neurosurgery, Scientific Reports | Textbooks: Elsevier & Springer Science
  • FAANS · FCNS · Member, Neuroscience and Spine Associates
99th
Healthgrades Percentile
Castle Connolly Top Doctor
5★
Google & Healthgrades
Consecutive Chief Resident
Patient Testimonials

What Patients Are Saying

All reviews are from verified patients who posted on Google or Healthgrades — completely uncensored and unedited.

“The most skilled, caring, and compassionate doctor you will ever meet.”

Mark V.
Verified Patient · Google Review

“The best surgeon by far. You won’t go wrong choosing Dr. Frenkel.”

Michael S.
Verified Patient · Google Review

“The Absolute BEST Neck & Back Surgeon!”

Antonio G.
Verified Patient · Healthgrades
Read All Patient Reviews

Your information is private and secure. We will never share your personal details.

Your Path to Relief

How It Works — 4 Simple Steps

From your first contact to your last follow-up, Dr. Frenkel’s team guides every step of your spinal fusion journey.

01

Schedule Your Consultation

Contact Dr. Frenkel at frenkelmd.com/contact/ or call (239) 649-1662. Out-of-town patients — including those seeking CemLIF™ — can inquire about the Concierge Program at frenkelmd.com/concierge-contact-form/. Telehealth available.

02

Imaging Review & Personalized Plan

Bring your MRI, CT, or X-rays. Dr. Frenkel reviews your imaging thoroughly, performs a complete neurological examination, and presents a clear, honest plan. You’ll understand exactly what is happening in your spine and what options — including CemLIF™ — are appropriate for you.

03

Fusion Surgery

Whether your case calls for CemLIF™, ALIF, LLIF, ACDF, or complex multi-level reconstruction, every procedure is performed with robotic assistance and augmented reality navigation — precision that sets Dr. Frenkel’s outcomes apart.

04

Recovery & Long-Term Support

Dr. Frenkel personally contacts families after surgery. His Nurse Practitioners handle all post-operative questions. Concierge patients have direct email access throughout recovery. Your care does not end in the operating room.

Frequently Asked Questions

Common Questions About Spinal Fusion & Dr. Frenkel

QWhat is spinal fusion surgery and when is it needed?
Spinal fusion permanently joins two or more vertebrae, eliminating painful motion between them and stabilizing the spine. It is recommended when instability — not just nerve compression — is part of the problem. Common indications include spondylolisthesis, degenerative disc disease with instability, spinal stenosis with instability, scoliosis, and failed prior surgery.
QWhat is CemLIF™ and am I a candidate?
CemLIF™ is a patented, rod-less, screw-less lumbar fusion technique invented by Dr. Frenkel — unavailable at any other practice. It delivers highly stable fusion without traditional hardware constructs. Whether CemLIF™ is appropriate depends on your specific anatomy, spinal level, and diagnosis, and is determined during a thorough consultation and imaging review. Learn more at cemlif.com.
QWhat is the difference between ALIF, PLIF, LLIF, and ACDF?
These are different approaches to spinal fusion: ALIF approaches the lumbar spine from the front; PLIF/TLIF from the back; LLIF/XLIF from the side; and ACDF fuses the cervical spine through the front of the neck. Dr. Frenkel selects the most appropriate approach based on your spinal level, anatomy, and clinical situation — ensuring each patient receives the technique best suited to their individual case.
QDoes Dr. Frenkel treat failed prior fusion (revision surgery)?
Yes. Dr. Frenkel regularly receives referrals from other surgeons for failed prior fusion, pseudarthrosis (failed fusion healing), adjacent segment disease, and complex revision cases. His patented CemLIF™ technique and augmented reality navigation make him uniquely equipped for revision scenarios where prior hardware creates additional complexity.
QWhat makes Dr. Frenkel different from other fusion surgeons?
Dr. Frenkel invented CemLIF™ — a fusion technique no other surgeon in the world performs. He was the first to use augmented reality in spine surgery. He holds one of the highest Neurosurgery Board scores in the country, was Chief Resident twice at Wake Forest, and is a Castle Connolly Top Doctor 2024–2026. Other spine surgeons refer their most complex fusion cases to him.
QCan I seek a second opinion on a fusion recommendation?
Absolutely. Dr. Frenkel welcomes patients seeking a second opinion on a fusion recommendation. He will conduct a thorough review of your imaging and provide an honest, independent assessment — including whether fusion is truly necessary, which type is most appropriate, and whether CemLIF™ or another innovative approach may be suitable for your case. No referral needed.
QCan I travel to Naples for spinal fusion surgery?
Yes. Dr. Frenkel’s Concierge Spinal Surgery Program is specifically designed for out-of-state and international patients. It includes telehealth consultations, travel and logistics coordination, VIP clinic access, and transparent cost information. Many patients travel to Naples specifically to access CemLIF™ — which is not available anywhere else. Inquire about the Concierge Program →
QWhere is Dr. Frenkel’s practice located?
Dr. Frenkel’s practice is inside Physicians Regional Medical Center, 6101 Pine Ridge Road, Naples, Florida 34119. He serves patients throughout Naples, Bonita Springs, Marco Island, Fort Myers, Estero, and Southwest Florida — and patients nationwide through the Concierge Spinal Surgery Program. Phone: (239) 649-1662.
Location & Contact

Visit Dr. Frenkel in Naples, Florida

Serving Naples, Southwest Florida, and patients nationwide through the Concierge Spinal Surgery Program.

Office Address

Inside Physicians Regional Medical Center
6101 Pine Ridge Road
Naples, Florida 34119

Phone & Fax

(239) 649-1662 (main)  ·  (239) 649-7053 (fax)

Schedule & Contact

Schedule Online — Local Patients →
Concierge Program Inquiry →
CemLIF™ Information →

Areas Served

Naples · Bonita Springs · Marco Island · Fort Myers · Estero · Collier County · Southwest Florida
Out-of-state & international patients served via Concierge Program

Recommended Accommodations for Traveling Patients

  • The Ritz-Carlton Naples — oceanfront luxury
  • Inn on Fifth — downtown Naples boutique hotel
  • Innovation Hotel — adjacent to the Surgery Center of Naples
Dr. Mark Frenkel MD — Neuroscience and Spine Associates

6101 Pine Ridge Road, Naples, FL 34119
Inside Physicians Regional Medical Center

Open in Google Maps →

You Deserve the Best Possible Outcome from Your Spinal Fusion — Not Just an Average One

Whether you’re considering your first fusion, seeking a second opinion, or recovering from a procedure that didn’t deliver the results you were promised — Dr. Frenkel’s team is ready to review your imaging and give you a clear, honest plan. As the inventor of CemLIF™ and a Castle Connolly Top Doctor three years running, Dr. Frenkel brings surgical capabilities available nowhere else. His schedule fills quickly. Contact his office today.